A-kinase anchor protein 14 (AKAP14)

About A-kinase anchor protein 14

A-kinase anchor protein 14 (AKAP14) is a protein from Homo sapiens identified by UniProt accession Q86UN6, 197 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.

Target properties

Protein name	A-kinase anchor protein 14
UniProt accession	Q86UN6
Gene	AKAP14
Organism	Homo sapiens
Length	197 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86UN6-F1	alphafold	PREDICTED	78.10	—

Amino-acid sequence (197 residues)

MSETQNSTSQ KAMDEDNKAA SQTMPNTQDK NYEDELTQVA LALVEDVINY AVKIVEEERN PLKNIKWMTH GEFTVEKGLK QIDEYFSKCV SKKCWAHGVE FVERKDLIHS FLYIYYVHWS ISTADLPVAR ISAGTYFTMK VSKTKPPDAP IVVSYVGDHQ ALVHRPGMVR FRENWQKNLT DAKYSFMESF PFLFNRV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards