Tachykinin-4 (TAC4)

About Tachykinin-4

Tachykinin-4 (TAC4) is a protein from Homo sapiens identified by UniProt accession Q86UU9, 113 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.

Target properties

Protein name	Tachykinin-4
UniProt accession	Q86UU9
Gene	TAC4
Organism	Homo sapiens
Length	113 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (38)

Diseases linked to this target (Open Targets).

blood urea nitrogen measurement · score 0.30
alkaline phosphatase measurement · score 0.28
balding measurement · score 0.23
mean reticulocyte volume · score 0.22
mean corpuscular volume · score 0.22
blood phosphate measurement · score 0.19
serum urea measurement · score 0.16
COVID-19 · score 0.08
sex hormone-binding globulin measurement · score 0.07
platelet count · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86UU9-F1	alphafold	PREDICTED	56.23	—

Amino-acid sequence (113 residues)

MLPCLALLLL MELSVCTVAG DGGEEQTLST EAETWVIVAL EEGAGPSIQL QLQEVKTGKA SQFFGLMGKR VGGRPLIQPR RKKAYQLEHT FQGLLGKRSL FTEGREDEAQ GSE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards