Organic solute transporter subunit beta (SLC51B)

About Organic solute transporter subunit beta

Organic solute transporter subunit beta (SLC51B) is a protein from Homo sapiens identified by UniProt accession Q86UW2, 128 residues long. MolForge cross-references it against 0 known binders and 53 disease associations.

Target properties

Protein name	Organic solute transporter subunit beta
UniProt accession	Q86UW2
Gene	SLC51B
Organism	Homo sapiens
Length	128 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (53)

Diseases linked to this target (Open Targets).

Diarrhea · score 0.27
cholestasis · score 0.27
FEV/FVC ratio · score 0.26
white matter hyperintensity measurement · score 0.18
body height · score 0.05
Barrett's esophagus · score 0.04
dehydrated hereditary stomatocytosis · score 0.04
hemoglobin D disease · score 0.04
congenital dyserythropoietic anemia type 4 · score 0.04
Congenital dyserythropoietic anemia type IV · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86UW2-F1	alphafold	PREDICTED	67.50	—

Amino-acid sequence (128 residues)

MEHSEGAPGD PAGTVVPQEL LEEMLWFFRV EDASPWNHSI LALAAVVVII SMVLLGRSIQ ASRKEKMQPP EKETPEVLHL DEAKDHNSLN NLRETLLSEK PNLAQVELEL KERDVLSVFL PDVPETES

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards