About Metalloprotease TIKI1
Metalloprotease TIKI1 (TRABD2A) is a protein
from Homo sapiens identified by UniProt accession
Q86V40, 505 residues long.
MolForge cross-references it against 0 known binders and
20 disease associations.
Target properties
| Protein name | Metalloprotease TIKI1 |
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| UniProt accession | Q86V40 |
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| Gene | TRABD2A |
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| Organism | Homo sapiens |
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| Length | 505 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86V40-F1 | alphafold | PREDICTED | 68.85 | — |
Amino-acid sequence (505 residues)
MSPWSWFLLQ TLCLLPTGAA SRRGAPGTAN CELKPQQSEL NSFLWTIKRD PPSYFFGTIH VPYTRVWDFI PDNSKEAFLQ SSIVYFELDL TDPYTISALT SCQMLPQGEN LQDVLPRDIY CRLKRHLEYV KLMMPLWMTP DQRGKGLYAD YLFNAIAGNW ERKRPVWVML MVNSLTEVDI KSRGVPVLDL FLAQEAERLR KQTGAVEKVE EQCHPLNGLN FSQVIFALNQ TLLQQESLRA GSLQIPYTTE DLIKHYNCGD LSSVILSHDS SQVPNFINAT LPPQERITAQ EIDSYLRREL IYKRNERIGK RVKALLEEFP DKGFFFAFGA GHFMGNNTVL DVLRREGYEV EHAPAGRPIH KGKSKKTSTR PTLSTIFAPK VPTLEVPAPE AVSSGHSTLP PLVSRPGSAD TPSEAEQRFR KKRRRSQRRP RLRQFSDLWV RLEESDIVPQ LQVPVLDRHI STELRLPRRG HSHHSQMVAS SACLSLWTPV FWVLVLAFQT ETPLL
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