Protein FAM124A (FAM124A)

About Protein FAM124A

Protein FAM124A (FAM124A) is a protein from Homo sapiens identified by UniProt accession Q86V42, 546 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.

Target properties

Protein name	Protein FAM124A
UniProt accession	Q86V42
Gene	FAM124A
Organism	Homo sapiens
Length	546 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (29)

Diseases linked to this target (Open Targets).

Abnormality of refraction · score 0.31
Nasal Cavity Polyp · score 0.20
demyelinating disease · score 0.06
body height · score 0.05
facial morphology measurement · score 0.04
idiopathic hypereosinophilic syndrome · score 0.04
hemoglobin H disease · score 0.03
dominant beta-thalassemia · score 0.03
glycoprotein storage disease · score 0.03
hemoglobin C-beta-thalassemia syndrome · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86V42-F1	alphafold	PREDICTED	62.25	—

Amino-acid sequence (546 residues)

MDPKAGGGGE EDDCVDSGAE TGGSDYSHLS STSSELSVEE AQDPFLVSIH IIADPGESQP LQEAIDNVLA WIHPDLPLFR VSERRASRRR RKPPKGAQPA LAVVLFLQEE YGEEQILQLH RTLQQPPWRH HHTEQVHGRF LPYLPCSQDF FTLAPGTPLW AIRPVHYGKE IVRFTVYCRY DNYADSLRFY QLILRRSPSQ KKADFCIFPI FSNLDVDIQF SLKRLPCDQC PVPTDSSVLE FRVRDIGELV PLLPNPCSPI SEGRWQTEDH DGNKILLQAQ RVHKKFPKPG RVHHASEKKR HSTPLPSTAV PSHTPGSSQQ SPLNSPHPGP IRTGLPPGHQ QEFAGRANST PNPPWSFQRS KSLFCLPTGG PSLASSAEPQ WFSNTGAPGH RASEWRHGHL LSIDDLEGAQ ETDVDTGLRL SSSDLSVVSA YSAPSRFCST VETPLPSERC SSHWAAHKDS REGPLPTVSR VTTEASWASL PFFTKRSSSS SATARAAPPA PSTSTLTDSS PQLPCDTPKV KQTDGDMPPP PGSAGPGDND MEEFYI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards