Serine/threonine-protein kinase pim-3 (PIM3)

About Serine/threonine-protein kinase pim-3

Serine/threonine-protein kinase pim-3 (PIM3) is a protein from Homo sapiens identified by UniProt accession Q86V86, 326 residues long. MolForge cross-references it against 0 known binders and 119 disease associations.

Target properties

Protein name	Serine/threonine-protein kinase pim-3
UniProt accession	Q86V86
Gene	PIM3
Organism	Homo sapiens
Length	326 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (4)

DrugCentral-linked approved drugs that act on this protein.

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86V86-F1	alphafold	PREDICTED	84.47	—

Amino-acid sequence (326 residues)

MLLSKFGSLA HLCGPGGVDH LPVKILQPAK ADKESFEKAY QVGAVLGSGG FGTVYAGSRI ADGLPVAVKH VVKERVTEWG SLGGATVPLE VVLLRKVGAA GGARGVIRLL DWFERPDGFL LVLERPEPAQ DLFDFITERG ALDEPLARRF FAQVLAAVRH CHSCGVVHRD IKDENLLVDL RSGELKLIDF GSGALLKDTV YTDFDGTRVY SPPEWIRYHR YHGRSATVWS LGVLLYDMVC GDIPFEQDEE ILRGRLLFRR RVSPECQQLI RWCLSLRPSE RPSLDQIAAH PWMLGADGGV PESCDLRLCT LDPDDVASTT SSSESL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards