About Magnesium-dependent phosphatase 1
Magnesium-dependent phosphatase 1 (MDP1) is a protein
from Homo sapiens identified by UniProt accession
Q86V88, 176 residues long.
MolForge cross-references it against 0 known binders and
16 disease associations.
Target properties
| Protein name | Magnesium-dependent phosphatase 1 |
|---|
| UniProt accession | Q86V88 |
|---|
| Gene | MDP1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 176 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (16)
Diseases linked to this target (Open Targets).
- Familial prostate cancer · score 0.11
- prostate cancer · score 0.11
- prostate carcinoma · score 0.11
- smoking behaviour measurement · score 0.07
- systolic blood pressure · score 0.07
- mean corpuscular volume · score 0.03
- platelet count · score 0.03
- red blood cell density measurement · score 0.03
- uterine fibroid · score 0.03
- mean corpuscular hemoglobin · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86V88-F1 | alphafold | PREDICTED | 93.63 | — |
Amino-acid sequence (176 residues)
MARLPKLAVF DLDYTLWPFW VDTHVDPPFH KSSDGTVRDR RGQDVRLYPE VPEVLKRLQS LGVPGAAASR TSEIEGANQL LELFDLFRYF VHREIYPGSK ITHFERLQQK TGIPFSQMIF FDDERRNIVD VSKLGVTCIH IQNGMNLQTL SQGLETFAKA QTGPLRSSLE ESPFEA
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