About Myb-related transcription factor, partner of profilin
Myb-related transcription factor, partner of profilin (MYPOP) is a protein
from Homo sapiens identified by UniProt accession
Q86VE0, 399 residues long.
MolForge cross-references it against 0 known binders and
24 disease associations.
Target properties
| Protein name | Myb-related transcription factor, partner of profilin |
|---|
| UniProt accession | Q86VE0 |
|---|
| Gene | MYPOP |
|---|
| Organism | Homo sapiens |
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| Length | 399 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (24)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- mean corpuscular hemoglobin concentration · score 0.29
- testosterone measurement · score 0.25
- C-reactive protein measurement · score 0.21
- mean corpuscular volume · score 0.21
- mean corpuscular hemoglobin · score 0.18
- bilirubin measurement · score 0.18
- apolipoprotein A 1 measurement · score 0.17
- Red cell distribution width · score 0.16
- osteoarthritis, hand · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86VE0-F1 | alphafold | PREDICTED | 64.73 | — |
Amino-acid sequence (399 residues)
MASAAAGEAE ETTRLRKPRF SFEENQILIR EVRAHYPQLY GAQSRRVSVA ERRRVWDGIA AKINGITSWK RTGQEVQKRW NDFKRRTKEK LARVPHSTQG AGPAAEDAFS AEEETIFAIL GPGVAAPGAG AGAEEPPAAP SSQPPPPSAC PQRYVLSEDR REDRRADTSA HSKAGSSSPE PWARPSCTPQ EGGCPRPKER ESPPPSALQP VQLPRLALSP PPPAPPLPPP PPLAQVAPSP PSPPPPPRPP PTLSASDPSL DFLRAQQETA NAIRELAGTL RQGLAKLSEA LSALLPLLPG TPVDSLPPPL PPPPPPPPPP RPVLPPPAPK VEITPEPVSV VAAVVDGAVV AARGVIIAPR SEEGAPRPPP APLPPHDSPP HKRRKGFPTR KRRGRWKSP
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