About Zinc finger CCCH domain-containing protein 18
Zinc finger CCCH domain-containing protein 18 (ZC3H18) is a protein
from Homo sapiens identified by UniProt accession
Q86VM9, 953 residues long.
MolForge cross-references it against 0 known binders and
30 disease associations.
Target properties
| Protein name | Zinc finger CCCH domain-containing protein 18 |
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| UniProt accession | Q86VM9 |
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| Gene | ZC3H18 |
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| Organism | Homo sapiens |
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| Length | 953 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86VM9-F1 | alphafold | PREDICTED | 51.78 | — |
Amino-acid sequence (953 residues)
MDVAESPERD PHSPEDEEQP QGLSDDDILR DSGSDQDLDG AGVRASDLED EESAARGPSQ EEEDNHSDEE DRASEPKSQD QDSEVNELSR GPTSSPCEEE GDEGEEDRTS DLRDEASSVT RELDEHELDY DEEVPEEPAP AVQEDEAEKA GAEDDEEKGE GTPREEGKAG VQSVGEKESL EAAKEKKKED DDGEIDDGEI DDDDLEEGEV KDPSDRKVRP RPTCRFFMKG NCTWGMNCRF IHPGVNDKGN YSLITKADPF PPNGAPPLGP HPLMPANPWG GPVVDEILPP PPPEPPTESA WERGLRHAKE VLKKATIRKE QEPDFEEKRF TVTIGEDERE FDKENEVFRD WNSRIPRDVR DTVLEPYADP YYDYEIERFW RGGQYENFRV QYTETEPYHN YRERERERER ENRQRERERE RERDRERERR QRERERERER ERDKERQRRK EEWERERAKR DEKDRQHRDR DREKEREKEK GKPKPRSPQP PSRQAEPPKK EAATTGPQVK RADEWKDPWR RSKSPKKKLG VSVSPSRARR RRKTSASSAS ASNSSRSSSR SSSYSGSGSS RSRSRSSSYS SYSSRSSRHS SFSGSRSRSR SFSSSPSPSP TPSPHRPSIR TKGEPAPPPG KAGEKSVKKP APPPAPPQAT KTTAPVPEPT KPGDPREARR KERPARTPPR RRTLSGSGSG SGSSYSGSSS RSRSLSVSSV SSVSSATSSS SSAHSVDSED MYADLASPVS SASSRSPAPA QTRKEKGKSK KEDGVKEEKR KRDSSTQPPK SAKPPAGGKS SQQPSTPQQA PPGQPQQGTF VAHKEIKLTL LNKAADKGSR KRYEPSDKDR QSPPPAKRPN TSPDRGSRDR KSGGRLGSPK PERQRGQNSK APAAPADRKR QLSPQSKSSS KVTSVPGKAS DPGAASTKSG KASTLSRREE LLKQLKAVED AIARKRAKIP GKA
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