About V-set and immunoglobulin domain-containing protein 10-like
V-set and immunoglobulin domain-containing protein 10-like (VSIG10L) is a protein
from Homo sapiens identified by UniProt accession
Q86VR7, 867 residues long.
MolForge cross-references it against 0 known binders and
21 disease associations.
Target properties
| Protein name | V-set and immunoglobulin domain-containing protein 10-like |
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| UniProt accession | Q86VR7 |
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| Gene | VSIG10L |
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| Organism | Homo sapiens |
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| Length | 867 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (21)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.25
- esophageal squamous cell carcinoma · score 0.04
- body mass index · score 0.04
- blood protein measurement · score 0.04
- esophageal adenocarcinoma · score 0.03
- myeloid cell surface antigen CD33 measurement · score 0.03
- HbA1c measurement · score 0.03
- diet measurement · score 0.03
- body height · score 0.03
- oral squamous cell carcinoma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86VR7-F1 | alphafold | PREDICTED | 70.02 | — |
Amino-acid sequence (867 residues)
MDNPQALPLF LLLASLVGIL TLRASSGLQQ TNFSSAFSSD SKSSSQGLGV EVPSIKPPSW KVPDQFLDSK ASAGISDSSW FPEALSSNMS GSFWSNVSAE GQDLSPVSPF SETPGSEVFP DISDPQVPAK DPKPSFTVKT PASNISTQVS HTKLSVEAPD SKFSPDDMDL KLSAQSPESK FSAETHSAAS FPQQVGGPLA VLVGTTIRLP LVPIPNPGPP TSLVVWRRGS KVLAAGGLGP GAPLISLDPA HRDHLRFDQA RGVLELASAQ LDDAGVYTAE VIRAGVSQQT HEFTVGVYEP LPQLSVQPKA PETEEGAAEL RLRCLGWGPG RGELSWSRDG RALEAAESEG AETPRMRSEG DQLLIVRPVR SDHARYTCRV RSPFGHREAA ADVSVFYGPD PPTITVSSDR DAAPARFVTA GSNVTLRCAA ASRPPADITW SLADPAEAAV PAGSRLLLPA VGPGHAGTYA CLAANPRTGR RRRSLLNLTV ADLPPGAPQC SVEGGPGDRS LRFRCSWPGG APAASLQFQG LPEGIRAGPV SSVLLAAVPA HPRLSGVPIT CLARHLVATR TCTVTPEAPR EVLLHPLVAE TRLGEAEVAL EASGCPPPSR ASWAREGRPL APGGGSRLRL SQDGRKLHIG NFSLDWDLGN YSVLCSGALG AGGDQITLIG PSISSWRLQR ARDAAVLTWD VERGALISSF EIQAWPDGPA LGRTSTYRDW VSLLILGPQE RSAVVPLPPR NPGTWTFRIL PILGGQPGTP SQSRVYRAGP TLSHGAIAGI VLGSLLGLAL LAVLLLLCIC CLCRFRGKTP EKKKHPSTLV PVVTPSEKKM HSVTPVEISW PLDLKVPLED HSSTRAYQAQ TPVQLSL
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