About COMM domain-containing protein 7
COMM domain-containing protein 7 (COMMD7) is a protein
from Homo sapiens identified by UniProt accession
Q86VX2, 200 residues long.
MolForge cross-references it against 0 known binders and
68 disease associations.
Target properties
| Protein name | COMM domain-containing protein 7 |
|---|
| UniProt accession | Q86VX2 |
|---|
| Gene | COMMD7 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 200 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (68)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.42
- birth weight · score 0.24
- blood protein measurement · score 0.19
- alcohol consumption measurement · score 0.15
- mean corpuscular volume · score 0.15
- basophil count · score 0.14
- lymphocyte:monocyte ratio · score 0.13
- erythrocyte count · score 0.12
- prostate carcinoma · score 0.10
- hepatocellular carcinoma · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86VX2-F1 | alphafold | PREDICTED | 84.69 | — |
Amino-acid sequence (200 residues)
MGRLHCTEDP VPEAVGGDMQ QLNQLGAQQF SALTEVLFHF LTEPKEVERF LAQLSEFATT NQISLGSLRS IVKSLLLVPN GALKKSLTAK QVQADFITLG LSEEKATYFS EKWKQNAPTL ARWAIGQTLM INQLIDMEWK FGVTSGSSEL EKVGSIFLQL KLVVKKGNQT ENVYIELTLP QFYSFLHEME RVRTSMECFC
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