About Juxtaposed with another zinc finger protein 1
Juxtaposed with another zinc finger protein 1 (JAZF1) is a protein
from Homo sapiens identified by UniProt accession
Q86VZ6, 243 residues long.
MolForge cross-references it against 0 known binders and
329 disease associations.
Target properties
| Protein name | Juxtaposed with another zinc finger protein 1 |
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| UniProt accession | Q86VZ6 |
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| Gene | JAZF1 |
|---|
| Organism | Homo sapiens |
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| Length | 243 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (329)
Diseases linked to this target (Open Targets).
- type 2 diabetes mellitus · score 0.53
- prostate carcinoma · score 0.51
- BMI-adjusted waist circumference · score 0.51
- body height · score 0.50
- asthma · score 0.50
- diabetes mellitus · score 0.49
- neurodegenerative disease · score 0.49
- lean body mass · score 0.48
- multiple sclerosis · score 0.48
- BMI-adjusted waist-hip ratio · score 0.48
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86VZ6-F1 | alphafold | PREDICTED | 69.50 | — |
Amino-acid sequence (243 residues)
MTGIAAASFF SNTCRFGGCG LHFPTLADLI EHIEDNHIDT DPRVLEKQEL QQPTYVALSY INRFMTDAAR REQESLKKKI QPKLSLTLSS SVSRGNVSTP PRHSSGSLTP PVTPPITPSS SFRSSTPTGS EYDEEEVDYE ESDSDESWTT ESAISSEAIL SSMCMNGGEE KPFACPVPGC KKRYKNVNGI KYHAKNGHRT QIRVRKPFKC RCGKSYKTAQ GLRHHTINFH PPVSAEIIRK MQQ
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