About Zinc finger and SCAN domain-containing protein 30
Zinc finger and SCAN domain-containing protein 30 (ZSCAN30) is a protein
from Homo sapiens identified by UniProt accession
Q86W11, 494 residues long.
MolForge cross-references it against 0 known binders and
16 disease associations.
Target properties
| Protein name | Zinc finger and SCAN domain-containing protein 30 |
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| UniProt accession | Q86W11 |
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| Gene | ZSCAN30 |
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| Organism | Homo sapiens |
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| Length | 494 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (16)
Diseases linked to this target (Open Targets).
- mathematical ability · score 0.28
- appendicular lean mass · score 0.17
- creatinine measurement · score 0.05
- protein measurement · score 0.04
- wellbeing measurement · score 0.03
- electrocardiography · score 0.03
- cortical surface area measurement · score 0.03
- cortical thickness · score 0.03
- adolescent idiopathic scoliosis · score 0.03
- depressive symptom measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86W11-F1 | alphafold | PREDICTED | 64.28 | — |
Amino-acid sequence (494 residues)
MSGEATVLAY HAPEEQEGLL VVKVEEENYV LDQDFGLQEN PWSQEVFRQK FRQFSYSDST GPREALSRLR ELCCQWLRPE VHSKEQILEL LMLEQFLAIL PEELQAWLRE HRPENGEEAV TMLEELEKEL EEPRQQDTTH GQEMFWQEMT STGALKSLSL NSPVQPLENQ CKTETQESQA FQERDGRMVA GKVLMAKQEI VECVASAAMI SPGKLPGETH SQRIAEEALG GLDNSKKQKG NAAGNKISQL PSQDRHFSLA TFNRRIPTEH SVLESHESEG SFSMNSNDIT QQSVDTREKL YECFDCGKAF CQSSKLIRHQ RIHTGERPYA CKECGKAFSL SSDLVRHQRI HSGEKPYECC ECGKAFRGSS ELIRHRRIHT GEKPYECGEC GKAFSRSSAL IQHKKIHTGD KSYECIACGK AFGRSSILIE HQRIHTGEKP YECNECGKSF NQSSALTQHQ RIHTGEKPYE CSECRKTFRH RSGLMQHQRT HTRV
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