About Protein FAM228A
Protein FAM228A (FAM228A) is a protein
from Homo sapiens identified by UniProt accession
Q86W67, 206 residues long.
MolForge cross-references it against 0 known binders and
18 disease associations.
Target properties
| Protein name | Protein FAM228A |
|---|
| UniProt accession | Q86W67 |
|---|
| Gene | FAM228A |
|---|
| Organism | Homo sapiens |
|---|
| Length | 206 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (18)
Diseases linked to this target (Open Targets).
- neutrophil count · score 0.34
- myeloid white cell count · score 0.25
- leukocyte count · score 0.22
- low density lipoprotein cholesterol measurement · score 0.13
- IGF-1 measurement · score 0.11
- total cholesterol measurement · score 0.11
- fat body mass · score 0.09
- appendicular lean mass · score 0.07
- body fat percentage · score 0.06
- granulocyte count · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86W67-F1 | alphafold | PREDICTED | 63.36 | — |
Amino-acid sequence (206 residues)
MAATKTASYD EHFRPEKLRE WPEPESVSLM EVLAREDIDE AVCAILFKEN SIVKVTVPPF VDPLFQRQQE VDEERRTGLQ CETGKRHSIK ELEEIEKARL HASSPYFTFT SHCVIPKEWH KASARARSKT YKYSPEKLIY ADKKQKRKEK KTADLSQAAF ERQFLSSKLS QKNKVGERKG LVSRGLGRGW HAGLCSTHEQ HILVPE
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