Ankyrin repeat domain-containing protein 46 (ANKRD46)

About Ankyrin repeat domain-containing protein 46

Ankyrin repeat domain-containing protein 46 (ANKRD46) is a protein from Homo sapiens identified by UniProt accession Q86W74, 228 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.

Target properties

Protein name	Ankyrin repeat domain-containing protein 46
UniProt accession	Q86W74
Gene	ANKRD46
Organism	Homo sapiens
Length	228 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86W74-F1	alphafold	PREDICTED	77.11	—

Amino-acid sequence (228 residues)

MSYVFVNDSS QTNVPLLQAC IDGDFNYSKR LLESGFDPNI RDSRGRTGLH LAAARGNVDI CQLLHKFGAD LLATDYQGNT ALHLCGHVDT IQFLVSNGLK IDICNHQGAT PLVLAKRRGV NKDVIRLLES LEEQEVKGFN RGTHSKLETM QTAESESAME SHSLLNPNLQ QGEGVLSSFR TTWQEFVEDL GFWRVLLLIF VIALLSLGIA YYVSGVLPFV ENQPELVH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards