Serine hydrolase BPHL (BPHL)

About Serine hydrolase BPHL

Serine hydrolase BPHL (BPHL) is a protein from Homo sapiens identified by UniProt accession Q86WA6, 291 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.

Target properties

Protein name	Serine hydrolase BPHL
UniProt accession	Q86WA6
Gene	BPHL
Organism	Homo sapiens
Length	291 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86WA6-F1	alphafold	PREDICTED	91.75	—

Amino-acid sequence (291 residues)

MVAVLGGRGV LRLRLLLSAL KPGIHVPRAG PAAAFGTSVT SAKVAVNGVQ LHYQQTGEGD HAVLLLPGML GSGETDFGPQ LKNLNKKLFT VVAWDPRGYG HSRPPDRDFP ADFFERDAKD AVDLMKALKF KKVSLLGWSD GGITALIAAA KYPSYIHKMV IWGANAYVTD EDSMIYEGIR DVSKWSERTR KPLEALYGYD YFARTCEKWV DGIRQFKHLP DGNICRHLLP RVQCPALIVH GEKDPLVPRF HADFIHKHVK GSRLHLMPEG KHNLHLRFAD EFNKLAEDFL Q

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards