Sodium-independent sulfate anion transporter (SLC26A11)

Homo sapiens — UniProt Q86WA9

Gene: SLC26A11Homo sapiensSwissProt reviewed

About Sodium-independent sulfate anion transporter

Sodium-independent sulfate anion transporter (SLC26A11) is a protein from Homo sapiens identified by UniProt accession Q86WA9, 606 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.

Target properties

Protein nameSodium-independent sulfate anion transporter
UniProt accessionQ86WA9
GeneSLC26A11
OrganismHomo sapiens
Length606 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (38)

Diseases linked to this target (Open Targets).

  • mucopolysaccharidosis type 3A · score 0.55
  • cutaneous melanoma · score 0.12
  • genetic disorder · score 0.12
  • mucopolysaccharidosis type 3 · score 0.12
  • psoriasis · score 0.09
  • attention deficit hyperactivity disorder · score 0.07
  • Stroke · score 0.05
  • Tourette syndrome · score 0.05
  • migraine disorder · score 0.05
  • attention deficit-hyperactivity disorder 8 · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q86WA9-F1alphafoldPREDICTED86.47—

Amino-acid sequence (606 residues)

MPSSVTALGQ ARSSGPGMAP SACCCSPAAL QRRLPILAWL PSYSLQWLKM DFVAGLSVGL TAIPQALAYA EVAGLPPQYG LYSAFMGCFV YFFLGTSRDV TLGPTAIMSL LVSFYTFHEP AYAVLLAFLS GCIQLAMGVL RLGFLLDFIS YPVIKGFTSA AAVTIGFGQI KNLLGLQNIP RPFFLQVYHT FLRIAETRVG DAVLGLVCML LLLVLKLMRD HVPPVHPEMP PGVRLSRGLV WAATTARNAL VVSFAALVAY SFEVTGYQPF ILTGETAEGL PPVRIPPFSV TTANGTISFT EMVQDMGAGL AVVPLMGLLE SIAVAKAFAS QNNYRIDANQ ELLAIGLTNM LGSLVSSYPV TGSFGRTAVN AQSGVCTPAG GLVTGVLVLL SLDYLTSLFY YIPKSALAAV IIMAVAPLFD TKIFRTLWRV KRLDLLPLCV TFLLCFWEVQ YGILAGALVS LLMLLHSAAR PETKVSEGPV LVLQPASGLS FPAMEALREE ILSRALEVSP PRCLVLECTH VCSIDYTVVL GLGELLQDFQ KQGVALAFVG LQVPVLRVLL SADLKGFQYF STLEEAEKHL RQEPGTQPYN IREDSILDQK VALLKA

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Quick facts

UniProtQ86WA9
GeneSLC26A11
OrganismHomo sapiens
Length606
Binders0
Diseases38
View on UniProt