Zinc finger C3HC-type protein 1 (ZC3HC1)

About Zinc finger C3HC-type protein 1

Zinc finger C3HC-type protein 1 (ZC3HC1) is a protein from Homo sapiens identified by UniProt accession Q86WB0, 502 residues long. MolForge cross-references it against 0 known binders and 191 disease associations.

Target properties

Protein name	Zinc finger C3HC-type protein 1
UniProt accession	Q86WB0
Gene	ZC3HC1
Organism	Homo sapiens
Length	502 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (191)

Diseases linked to this target (Open Targets).

cancer · score 0.46
neurodegenerative disease · score 0.45
coronary artery disease · score 0.40
hemoglobin measurement · score 0.38
platelet count · score 0.38
diastolic blood pressure · score 0.37
eosinophil count · score 0.37
sex hormone-binding globulin measurement · score 0.37
hematocrit · score 0.36
neutrophil count · score 0.36

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86WB0-F1	alphafold	PREDICTED	68.28	—

Amino-acid sequence (502 residues)

MAAPCEGQAF AVGVEKNWGA VVRSPEGTPQ KIRQLIDEGI APEEGGVDAK DTSATSQSVN GSPQAEQPSL ESTSKEAFFS RVETFSSLKW AGKPFELSPL VCAKYGWVTV ECDMLKCSSC QAFLCASLQP AFDFDRYKQR CAELKKALCT AHEKFCFWPD SPSPDRFGML PLDEPAILVS EFLDRFQSLC HLDLQLPSLR PEDLKTMCLT EDKISLLLHL LEDELDHRTD ERKTTIKLGS DIQVHVTACI LSVCGWACSS SLESMQLSLI TCSQCMRKVG LWGFQQIESS MTDLDASFGL TSSPIPGLEG RPERLPLVPE SPRRMMTRSQ DATFSPGSEQ AEKSPGPIVS RTRSWDSSSP VDRPEPEAAS PTTRTRPVTR SMGTGDTPGL EVPSSPLRKA KRARLCSSSS SDTSSRSFFD PTSQHRDWCP WVNITLGKES RENGGTEPDA SAPAEPGWKA VLTILLAHKQ SSQPAETDSM SLSEKSRKVF RIFRQWESLC SC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards