Protein unc-93 homolog A (UNC93A)

About Protein unc-93 homolog A

Protein unc-93 homolog A (UNC93A) is a protein from Homo sapiens identified by UniProt accession Q86WB7, 457 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.

Target properties

Protein name	Protein unc-93 homolog A
UniProt accession	Q86WB7
Gene	UNC93A
Organism	Homo sapiens
Length	457 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (21)

Diseases linked to this target (Open Targets).

serum metabolite measurement · score 0.44
urinary metabolite measurement · score 0.40
self reported educational attainment · score 0.05
Crohn's disease · score 0.04
non-small cell lung carcinoma · score 0.03
ovarian cancer · score 0.03
neoplasm · score 0.02
colorectal adenocarcinoma · score 0.02
psoriasis · score 0.02
colorectal cancer · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86WB7-F1	alphafold	PREDICTED	85.14	—

Amino-acid sequence (457 residues)

MDRSLRNVLV VSFGFLLLFT AYGGLQSLQS SLYSEEGLGV TALSTLYGGM LLSSMFLPPL LIERLGCKGT IILSMCGYVA FSVGNFFASW YTLIPTSILL GLGAAPLWSA QCTYLTITGN THAEKAGKRG KDMVNQYFGI FFLIFQSSGV WGNLISSLVF GQTPSQETLP EEQLTSCGAS DCLMATTTTN STQRPSQQLV YTLLGIYTGS GVLAVLMIAA FLQPIRDVQR ESEGEKKSVP FWSTLLSTFK LYRDKRLCLL ILLPLYSGLQ QGFLSSEYTR SYVTCTLGIQ FVGYVMICFS ATDALCSVLY GKVSQYTGRA VLYVLGAVTH VSCMIALLLW RPRADHLAVF FVFSGLWGVA DAVWQTQNNA LYGVLFEKSK EAAFANYRLW EALGFVIAFG YSMFLCVHVK LYILLGVLSL TMVAYGLVEC VESKNPIRPH APGQVNQAED EEIQTKM

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards