Serpin A9 (SERPINA9)

About Serpin A9

Serpin A9 (SERPINA9) is a protein from Homo sapiens identified by UniProt accession Q86WD7, 417 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.

Target properties

Protein name	Serpin A9
UniProt accession	Q86WD7
Gene	SERPINA9
Organism	Homo sapiens
Length	417 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (33)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.29
childhood trauma measurement · score 0.04
smoking behaviour measurement · score 0.04
diffuse large B-cell lymphoma · score 0.04
cortisol measurement · score 0.03
Crohn's disease · score 0.02
kallistatin measurement · score 0.02
osteosarcoma · score 0.02
Mantle cell lymphoma · score 0.01
marginal zone B-cell lymphoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86WD7-F1	alphafold	PREDICTED	86.12	—

Amino-acid sequence (417 residues)

MASYLYGVLF AVGLCAPIYC VSPANAPSAY PRPSSTKSTP ASQVYSLNTD FAFRLYRRLV LETPSQNIFF SPVSVSTSLA MLSLGAHSVT KTQILQGLGF NLTHTPESAI HQGFQHLVHS LTVPSKDLTL KMGSALFVKK ELQLQANFLG NVKRLYEAEV FSTDFSNPSI AQARINSHVK KKTQGKVVDI IQGLDLLTAM VLVNHIFFKA KWEKPFHPEY TRKNFPFLVG EQVTVHVPMM HQKEQFAFGV DTELNCFVLQ MDYKGDAVAF FVLPSKGKMR QLEQALSART LRKWSHSLQK RWIEVFIPRF SISASYNLET ILPKMGIQNV FDKNADFSGI AKRDSLQVSK ATHKAVLDVS EEGTEATAAT TTKFIVRSKD GPSYFTVSFN RTFLMMITNK ATDGILFLGK VENPTKS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards