Caytaxin (ATCAY)

About Caytaxin

Caytaxin (ATCAY) is a protein from Homo sapiens identified by UniProt accession Q86WG3, 371 residues long. MolForge cross-references it against 0 known binders and 332 disease associations.

Target properties

Protein name	Caytaxin
UniProt accession	Q86WG3
Gene	ATCAY
Organism	Homo sapiens
Length	371 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (332)

Diseases linked to this target (Open Targets).

Cayman type cerebellar ataxia · score 0.71
Cerebellar ataxia, Cayman type · score 0.47
genetic disorder · score 0.19
spinocerebellar ataxia type 23 · score 0.09
Spinocerebellar ataxia type 40 · score 0.09
Ataxia - oculomotor apraxia type 1 · score 0.08
Dysequilibrium syndrome · score 0.08
Rare hereditary ataxia · score 0.08
Intellectual disability-coarse face-macrocephaly-cerebellar hypotrophy syndrome · score 0.08
spinocerebellar ataxia type 35 · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86WG3-F1	alphafold	PREDICTED	69.59	—

Amino-acid sequence (371 residues)

MGTTEATLRM ENVDVKEEWQ DEDLPRPLPE ETGVELLGSP VEDTSSPPNT LNFNGAHRKR KTLVAPEINI SLDQSEGSLL SDDFLDTPDD LDINVDDIET PDETDSLEFL GNGNELEWED DTPVATAKNM PGDSADLFGD GTTEDGSAAN GRLWRTVIIG EQEHRIDLHM IRPYMKVVTH GGYYGEGLNA IIVFAACFLP DSSLPDYHYI MENLFLYVIS SLELLVAEDY MIVYLNGATP RRRMPGIGWL KKCYQMIDRR LRKNLKSLII VHPSWFIRTV LAISRPFISV KFINKIQYVH SLEDLEQLIP MEHVQIPDCV LQYEEERLKA RRESARPQPE FVLPRSEEKP EVAPVENRSA LVSEDQETSM S

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards