About Ras association domain-containing protein 3
Ras association domain-containing protein 3 (RASSF3) is a protein
from Homo sapiens identified by UniProt accession
Q86WH2, 238 residues long.
MolForge cross-references it against 0 known binders and
32 disease associations.
Target properties
| Protein name | Ras association domain-containing protein 3 |
|---|
| UniProt accession | Q86WH2 |
|---|
| Gene | RASSF3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 238 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (32)
Diseases linked to this target (Open Targets).
- platelet count · score 0.41
- mean platelet volume · score 0.40
- neurodegenerative disease · score 0.32
- neutrophil count · score 0.28
- leukocyte count · score 0.27
- FEV/FVC ratio · score 0.24
- myeloid white cell count · score 0.23
- prostate carcinoma · score 0.23
- resting heart rate · score 0.20
- lymphocyte percentage of leukocytes · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86WH2-F1 | alphafold | PREDICTED | 79.08 | — |
Amino-acid sequence (238 residues)
MSSGYSSLEE DAEDFFFTAR TSFFRRAPQG KPRSGQQDVE KEKETHSYLS KEEIKEKVHK YNLAVTDKLK MTLNSNGIYT GFIKVQMELC KPPQTSPNSG KLSPSSNGCM NTLHISSTNT VGEVIEALLK KFLVTESPAK FALYKRCHRE DQVYACKLSD REHPLYLRLV AGPRTDTLSF VLREHEIGEW EAFSLPELQN FLRILDKEED EQLQNLKRRY TAYRQKLEEA LREVWKPD
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