LHFPL tetraspan subfamily member 1 protein (LHFPL1)

About LHFPL tetraspan subfamily member 1 protein

LHFPL tetraspan subfamily member 1 protein (LHFPL1) is a protein from Homo sapiens identified by UniProt accession Q86WI0, 220 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.

Target properties

Protein name	LHFPL tetraspan subfamily member 1 protein
UniProt accession	Q86WI0
Gene	LHFPL1
Organism	Homo sapiens
Length	220 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (4)

Diseases linked to this target (Open Targets).

erythrocyte count · score 0.02
hematocrit · score 0.02
hemoglobin measurement · score 0.02
liver and intrahepatic bile duct neoplasm · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86WI0-F1	alphafold	PREDICTED	89.71	—

Amino-acid sequence (220 residues)

MRSSLTMVGT LWAFLSLVTA VTSSTSYFLP YWLFGSQMGK PVSFSTFRRC NYPVRGEGHS LIMVEECGRY ASFNAIPSLA WQMCTVVTGA GCALLLLVAL AAVLGCCMEE LISRMMGRCM GAAQFVGGLL ISSGCALYPL GWNSPEIMQT CGNVSNQFQL GTCRLGWAYY CAGGGAAAAM LICTWLSCFA GRNPKPVILV ESIMRNTNSY AMELDHCLKP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards