About Interferon epsilon
Interferon epsilon (IFNE) is a protein
from Homo sapiens identified by UniProt accession
Q86WN2, 208 residues long.
MolForge cross-references it against 0 known binders and
133 disease associations.
Target properties
| Protein name | Interferon epsilon |
|---|
| UniProt accession | Q86WN2 |
|---|
| Gene | IFNE |
|---|
| Organism | Homo sapiens |
|---|
| Length | 208 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (133)
Diseases linked to this target (Open Targets).
- hypothyroidism · score 0.32
- Thyroid preparation use measurement · score 0.27
- Hashimoto's thyroiditis · score 0.26
- thyroid disease · score 0.26
- macula measurement · score 0.24
- myxedema · score 0.22
- diabetes mellitus · score 0.21
- endocrine system disease · score 0.21
- drug use measurement · score 0.20
- squamous cell lung carcinoma · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86WN2-F1 | alphafold | PREDICTED | 81.55 | — |
Amino-acid sequence (208 residues)
MIIKHFFGTV LVLLASTTIF SLDLKLIIFQ QRQVNQESLK LLNKLQTLSI QQCLPHRKNF LLPQKSLSPQ QYQKGHTLAI LHEMLQQIFS LFRANISLDG WEENHTEKFL IQLHQQLEYL EALMGLEAEK LSGTLGSDNL RLQVKMYFRR IHDYLENQDY STCAWAIVQV EISRCLFFVF SLTEKLSKQG RPLNDMKQEL TTEFRSPR
Explore Interferon epsilon with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets