Proline and serine-rich protein 2 (PROSER2)

About Proline and serine-rich protein 2

Proline and serine-rich protein 2 (PROSER2) is a protein from Homo sapiens identified by UniProt accession Q86WR7, 435 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.

Target properties

Protein name	Proline and serine-rich protein 2
UniProt accession	Q86WR7
Gene	PROSER2
Organism	Homo sapiens
Length	435 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86WR7-F1	alphafold	PREDICTED	57.44	—

Amino-acid sequence (435 residues)

MPVTHRKSDA SDMNSDTSPS CRLRAFSRGG SLESRSSSSR SRSFTLDDES LKYLTHEEKD VLLFFEETID SLDEDFEEPV LCDGGVCCLC SPSLEESTSS PSEPEDVIDL VQPAPGAGEA EGLPEGTQAA GPAPAGKEHR KQDAETPPPP DPPAPETLLA PPPLPSTPDP PRRELRAPSP PVEHPRLLRS VPTPLVMAQK ISERMAGNEA LSPTSPFREG RPGEWRTPAA RGPRSGDPGP GPSHPAQPKA PRFPSNIIVT NGAAREPRRT LSRAAVSVQE RRAQVLATIH GHAGAFPAAG DAGEGAPGGG SSPERVARGR GLPGPAESLR AGGQAPRGPA LANGFPSAHE ALKSAPSSFA PAGKSLCFRP GPALPSTRAR QSFPGPRQPN GAQDWRRADS LPRPQGITVQ FAGRGSSEEA RREALRKLGL LRESS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards