About E3 ubiquitin-protein ligase TRIM69
E3 ubiquitin-protein ligase TRIM69 (TRIM69) is a protein
from Homo sapiens identified by UniProt accession
Q86WT6, 500 residues long.
MolForge cross-references it against 0 known binders and
36 disease associations.
Target properties
| Protein name | E3 ubiquitin-protein ligase TRIM69 |
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| UniProt accession | Q86WT6 |
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| Gene | TRIM69 |
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| Organism | Homo sapiens |
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| Length | 500 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86WT6-F1 | alphafold | PREDICTED | 88.27 | — |
Amino-acid sequence (500 residues)
MEVSTNPSSN IDPGDYVEMN DSITHLPSKV VIQDITMELH CPLCNDWFRD PLMLSCGHNF CEACIQDFWR LQAKETFCPE CKMLCQYNNC TFNPVLDKLV EKIKKLPLLK GHPQCPEHGE NLKLFSKPDG KLICFQCKDA RLSVGQSKEF LQISDAVHFF TEELAIQQGQ LETTLKELQT LRNMQKEAIA AHKENKLHLQ QHVSMEFLKL HQFLHSKEKD ILTELREEGK ALNEEMELNL SQLQEQCLLA KDMLVSIQAK TEQQNSFDFL KDITTLLHSL EQGMKVLATR ELISRKLNLG QYKGPIQYMV WREMQDTLCP GLSPLTLDPK TAHPNLVLSK SQTSVWHGDI KKIMPDDPER FDSSVAVLGS RGFTSGKWYW EVEVAKKTKW TVGVVRESII RKGSCPLTPE QGFWLLRLRN QTDLKALDLP SFSLTLTNNL DKVGIYLDYE GGQLSFYNAK TMTHIYTFSN TFMEKLYPYF CPCLNDGGEN KEPLHILHPQ
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