CST complex subunit TEN1 (TEN1)

About CST complex subunit TEN1

CST complex subunit TEN1 (TEN1) is a protein from Homo sapiens identified by UniProt accession Q86WV5, 123 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.

Target properties

Protein name	CST complex subunit TEN1
UniProt accession	Q86WV5
Gene	TEN1
Organism	Homo sapiens
Length	123 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (28)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.32
peroxisomal acyl-CoA oxidase deficiency · score 0.16
urinary metabolite measurement · score 0.09
lymphocyte count · score 0.08
cancer · score 0.05
rheumatic fever · score 0.04
white matter hyperintensity measurement · score 0.03
Abnormal sperm morphology · score 0.01
neoplasm · score 0.01
Invasive Breast Carcinoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86WV5-F1	alphafold	PREDICTED	93.59	—

Amino-acid sequence (123 residues)

MMLPKPGTYY LPWEVSAGQV PDGSTLRTFG RLCLYDMIQS RVTLMAQHGS DQHQVLVCTK LVEPFHAQVG SLYIVLGELQ HQQDRGSVVK ARVLTCVEGM NLPLLEQAIR EQRLYKQERG GSQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards