About Lipolysis-stimulated lipoprotein receptor
Lipolysis-stimulated lipoprotein receptor (LSR) is a protein
from Homo sapiens identified by UniProt accession
Q86X29, 649 residues long.
MolForge cross-references it against 0 known binders and
84 disease associations.
Target properties
| Protein name | Lipolysis-stimulated lipoprotein receptor |
|---|
| UniProt accession | Q86X29 |
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| Gene | LSR |
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| Organism | Homo sapiens |
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| Length | 649 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (84)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.34
- cutaneous melanoma · score 0.23
- lung adenocarcinoma · score 0.22
- Intellectual disability · score 0.18
- Short stature · score 0.18
- red blood cell density measurement · score 0.17
- lymphocyte count · score 0.15
- erythrocyte count · score 0.12
- lysosomal storage disease · score 0.11
- mean corpuscular volume · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86X29-F1 | alphafold | PREDICTED | 57.39 | — |
Amino-acid sequence (649 residues)
MQQDGLGVGT RNGSGKGRSV HPSWPWCAPR PLRYFGRDAR ARRAQTAAMA LLAGGLSRGL GSHPAAAGRD AVVFVWLLLS TWCTAPARAI QVTVSNPYHV VILFQPVTLP CTYQMTSTPT QPIVIWKYKS FCRDRIADAF SPASVDNQLN AQLAAGNPGY NPYVECQDSV RTVRVVATKQ GNAVTLGDYY QGRRITITGN ADLTFDQTAW GDSGVYYCSV VSAQDLQGNN EAYAELIVLG RTSGVAELLP GFQAGPIEDW LFVVVVCLAA FLIFLLLGIC WCQCCPHTCC CYVRCPCCPD KCCCPEALYA AGKAATSGVP SIYAPSTYAH LSPAKTPPPP AMIPMGPAYN GYPGGYPGDV DRSSSAGGQG SYVPLLRDTD SSVASEVRSG YRIQASQQDD SMRVLYYMEK ELANFDPSRP GPPSGRVERA MSEVTSLHED DWRSRPSRGP ALTPIRDEEW GGHSPRSPRG WDQEPAREQA GGGWRARRPR ARSVDALDDL TPPSTAESGS RSPTSNGGRS RAYMPPRSRS RDDLYDQDDS RDFPRSRDPH YDDFRSRERP PADPRSHHHR TRDPRDNGSR SGDLPYDGRL LEEAVRKKGS EERRRPHKEE EEEAYYPPAP PPYSETDSQA SRERRLKKNL ALSRESLVV
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