NAD(P)H pyrophosphatase NUDT13, mitochondrial (NUDT13)

About NAD(P)H pyrophosphatase NUDT13, mitochondrial

NAD(P)H pyrophosphatase NUDT13, mitochondrial (NUDT13) is a protein from Homo sapiens identified by UniProt accession Q86X67, 352 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.

Target properties

Protein name	NAD(P)H pyrophosphatase NUDT13, mitochondrial
UniProt accession	Q86X67
Gene	NUDT13
Organism	Homo sapiens
Length	352 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (27)

Diseases linked to this target (Open Targets).

total cholesterol measurement · score 0.11
systolic blood pressure · score 0.10
serum alanine aminotransferase measurement · score 0.08
body height · score 0.08
reticulocyte measurement · score 0.07
Familial exudative vitreoretinopathy · score 0.06
X-linked retinal dysplasia · score 0.05
severe early-childhood-onset retinal dystrophy · score 0.05
MODY · score 0.05
X-linked retinoschisis · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86X67-F1	alphafold	PREDICTED	88.53	—

Amino-acid sequence (352 residues)

MSLYCGIACR RKFFWCYRLL STYVTKTRYL FELKEDDDAC KKAQQTGAFY LFHSLAPLLQ TSAHQYLAPR HSLLELERLL GKFGQDAQRI EDSVLIGCSE QQEAWFALDL GLDSSFSISA SLHKPEMETE LKGSFIELRK ALFQLNARDA SLLSTAQALL RWHDAHQFCS RSGQPTKKNV AGSKRVCPSN NIIYYPQMAP VAITLVSDGT RCLLARQSSF PKGMYSALAG FCDIGESVEE TIRREVAEEV GLEVESLQYY ASQHWPFPSG SLMIACHATV KPGQTEIQVN LRELETAAWF SHDEVATALK RKGPYTQQQN GTFPFWLPPK LAISHQLIKE WVEKQTCSSL PA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards