COMM domain-containing protein 2 (COMMD2)

About COMM domain-containing protein 2

COMM domain-containing protein 2 (COMMD2) is a protein from Homo sapiens identified by UniProt accession Q86X83, 199 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.

Target properties

Protein name	COMM domain-containing protein 2
UniProt accession	Q86X83
Gene	COMMD2
Organism	Homo sapiens
Length	199 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86X83-F1	alphafold	PREDICTED	88.97	—

Amino-acid sequence (199 residues)

MLLELSEEHK EHLAFLPQVD SAVVAEFGRI AVEFLRRGAN PKIYEGAARK LNVSSDTVQH GVEGLTYLLT ESSKLMISEL DFQDSVFVLG FSEELNKLLL QLYLDNRKEI RTILSELAPS LPSYHNLEWR LDVQLASRSL RQQIKPAVTI KLHLNQNGDH NTKVLQTDPA TLLHLVQQLE QALEEMKTNH CRRVVRNIK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards