About Protein FAM131B
Protein FAM131B (FAM131B) is a protein
from Homo sapiens identified by UniProt accession
Q86XD5, 332 residues long.
MolForge cross-references it against 0 known binders and
95 disease associations.
Target properties
| Protein name | Protein FAM131B |
|---|
| UniProt accession | Q86XD5 |
|---|
| Gene | FAM131B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 332 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (95)
Diseases linked to this target (Open Targets).
- cancer · score 0.54
- lung adenocarcinoma · score 0.28
- colorectal adenocarcinoma · score 0.19
- melanoma · score 0.19
- hepatocellular carcinoma · score 0.18
- T-cell acute lymphoblastic leukemia · score 0.18
- breast carcinoma · score 0.18
- gastric carcinoma · score 0.18
- head and neck squamous cell carcinoma · score 0.18
- alveolar rhabdomyosarcoma · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86XD5-F1 | alphafold | PREDICTED | 55.14 | — |
Amino-acid sequence (332 residues)
MDSTSSLHGS SLHRPSTEQT RTDFSWDGIN LSMEDTTSIL PKLKRNSNAY GIGALAKSSF SGISRSMKDH VTKPTAMGQG RVAHMIEWQG WGKTPAVQPQ HSHESVRRDT DAYSDLSDGE KEARFLAGVM EQFAISEATL MAWSSMDGED MSVNSTQEPL GCNYSDNYQE LMDSQDALAQ APMDGWPHSY VSQGMYCLGS SDAWEASDQS LIASPATGSY LGPAFDDSQP SLHEMGPSQP ASGYSALEPP PLLGGDTDWA PGVGAVDLAR GPAEEEKRPL APEEEEDAGC RDLESLSPRE DPEMSTALSR KVSDVTSSGV QSFDEEEGEA NN
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