About Zinc finger protein 575
Zinc finger protein 575 (ZNF575) is a protein
from Homo sapiens identified by UniProt accession
Q86XF7, 245 residues long.
MolForge cross-references it against 0 known binders and
18 disease associations.
Target properties
| Protein name | Zinc finger protein 575 |
|---|
| UniProt accession | Q86XF7 |
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| Gene | ZNF575 |
|---|
| Organism | Homo sapiens |
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| Length | 245 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (18)
Diseases linked to this target (Open Targets).
- ethylmalonic encephalopathy · score 0.57
- body height · score 0.23
- genetic disorder · score 0.17
- neoplasm · score 0.07
- low density lipoprotein cholesterol measurement · score 0.07
- apolipoprotein B measurement · score 0.05
- forced expiratory volume · score 0.05
- platelet count · score 0.04
- calcium measurement · score 0.04
- appendicular lean mass · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86XF7-F1 | alphafold | PREDICTED | 74.29 | — |
Amino-acid sequence (245 residues)
MLERGAESAA GATDPSPTGK EPVTKEAPHQ GPPQKPSQSA PGPTASAGSP PRPRRRPPPQ RPHRCPDCDK AFSYPSKLAT HRLAHGGARP HPCPDCPKAF SYPSKLAAHR LTHSGARPHP CPHCPKSFGH RSKLAAHLWT HAPTRPYPCP DCPKSFCYPS KLAAHRHTHH ATDARPYPCP HCPKAFSFPS KLAAHRLCHD PPTAPGSQAT AWHRCSSCGQ AFGQRRLLLL HQRSHHQVEH KGERD
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