About Gastrokine-2
Gastrokine-2 (GKN2) is a protein
from Homo sapiens identified by UniProt accession
Q86XP6, 184 residues long.
MolForge cross-references it against 0 known binders and
107 disease associations.
Target properties
| Protein name | Gastrokine-2 |
|---|
| UniProt accession | Q86XP6 |
|---|
| Gene | GKN2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 184 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (107)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.45
- gut microbiome measurement · score 0.28
- neurodegenerative disease · score 0.26
- neoplasm · score 0.09
- lung adenocarcinoma · score 0.09
- non-small cell lung carcinoma · score 0.09
- gastric carcinoma · score 0.06
- gonorrhea · score 0.06
- gastric adenocarcinoma · score 0.06
- isolated agammaglobulinemia · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86XP6-F1 | alphafold | PREDICTED | 85.97 | — |
Amino-acid sequence (184 residues)
MKILVAFLVV LTIFGIQSHG YEVFNIISPS NNGGNVQETV TIDNEKNTAI INIHAGSCSS TTIFDYKHGY IASRVLSRRA CFILKMDHQN IPPLNNLQWY IYEKQALDNM FSSKYTWVKY NPLESLIKDV DWFLLGSPIE KLCKHIPLYK GEVVENTHNV GAGGCAKAGL LGILGISICA DIHV
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