About Protein Niban 3
Protein Niban 3 (NIBAN3) is a protein
from Homo sapiens identified by UniProt accession
Q86XR2, 697 residues long.
MolForge cross-references it against 0 known binders and
182 disease associations.
Target properties
| Protein name | Protein Niban 3 |
|---|
| UniProt accession | Q86XR2 |
|---|
| Gene | NIBAN3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 697 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (182)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.34
- leukocyte count · score 0.31
- myeloid white cell count · score 0.22
- common variable immunodeficiency · score 0.08
- isolated agammaglobulinemia · score 0.07
- ICF syndrome · score 0.07
- severe combined immunodeficiency due to CARD11 deficiency · score 0.06
- Hodgkins lymphoma · score 0.06
- classic Hodgkin lymphoma · score 0.06
- BENTA disease · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86XR2-F1 | alphafold | PREDICTED | 77.46 | — |
Amino-acid sequence (697 residues)
MGPDRKEVPL SRGTQAVVVG KGRGAPGDDS SMGGRPSSPL DKQQRQHLRG QVDTLLRNFL PCYRGQLAAS VLRQISRELG PQEPTGSQLL RSKKLPRVRE HRGPLTQLRG HPPRWQPIFC VLRGDGRLEW FSHKEEYENG GHCLGSTALT GYTLLTSQRE YLRLLDALCP ESLGDHTQEE PDSLLEVPVS FPLFLQHPFR RHLCFSAATR EAQHAWRLAL QGGIRLQGIV LQRSQAPAAR AFLDAVRLYR QHQGHFGDDD VTLGSDAEVL TAVLMREQLP ALRAQTLPGL RGAGRARAWA WTELLDAVHA AVLAGASAGL CAFQPEKDEL LASLEKTIRP DVDQLLRQRA RVAGRLRTDI RGPLESCLRR EVDPQLPRVV QTLLRTVEAS LEAVRTLLAQ GMDRLSHRLR QSPSGTRLRR EVYSFGEMPW DLALMQTCYR EAERSRGRLG QLAAPFGFLG MQSLVFGAQD LAQQLMADAV ATFLQLADQC LTTALNCDQA AQRLERVRGR VLKKFKSDSG LAQRRFIRGW GLCIFLPFVL SQLEPGCKKE LPEFEGDVLA VGSQALTTEG IYEDVIRGCL LQRIDQELKK TLGANDVSCT LDGCLEVPWE QEGAAPNLNL VSSFLAGRQA FTDFLCLPAK SSANWILAAS LLSCSCFRSG FHRDSRVFLV QLAEGLSHSL ETVSSHSVWS FRPTPRQ
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