Collagen alpha-1(XXIII) chain (COL23A1)

About Collagen alpha-1(XXIII) chain

Collagen alpha-1(XXIII) chain (COL23A1) is a protein from Homo sapiens identified by UniProt accession Q86Y22, 540 residues long. MolForge cross-references it against 0 known binders and 48 disease associations.

Target properties

Protein name	Collagen alpha-1(XXIII) chain
UniProt accession	Q86Y22
Gene	COL23A1
Organism	Homo sapiens
Length	540 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (48)

Diseases linked to this target (Open Targets).

prostate carcinoma · score 0.40
nose morphology measurement · score 0.33
balding measurement · score 0.28
breast adenocarcinoma · score 0.26
lung adenocarcinoma · score 0.18
insomnia · score 0.18
total blood protein measurement · score 0.18
gut microbiome measurement · score 0.15
DNA methylation · score 0.14
endometrial cancer · score 0.14

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86Y22-F1	alphafold	PREDICTED	58.90	—

Amino-acid sequence (540 residues)

MGPGERAGGG GDAGKGNAAG GGGGGRSATT AGSRAVSALC LLLSVGSAAA CLLLGVQAAA LQGRVAALEE ERELLRRAGP PGALDAWAEP HLERLLREKL DGLAKIRTAR EAPSECVCPP GPPGRRGKPG RRGDPGPPGQ SGRDGYPGPL GLDGKPGLPG PKGEKGAPGD FGPRGDQGQD GAAGPPGPPG PPGARGPPGD TGKDGPRGAQ GPAGPKGEPG QDGEMGPKGP PGPKGEPGVP GKKGDDGTPS QPGPPGPKGE PGSMGPRGEN GVDGAPGPKG EPGHRGTDGA AGPRGAPGLK GEQGDTVVID YDGRILDALK GPPGPQGPPG PPGIPGAKGE LGLPGAPGID GEKGPKGQKG DPGEPGPAGL KGEAGEMGLS GLPGADGLKG EKGESASDSL QESLAQLIVE PGPPGPPGPP GPMGLQGIQG PKGLDGAKGE KGASGERGPS GLPGPVGPPG LIGLPGTKGE KGRPGEPGLD GFPGPRGEKG DRSERGEKGE RGVPGRKGVK GQKGEPGPPG LDQPCPVGPD GLPVPGCWHK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards