About NUT family member 1
NUT family member 1 (NUTM1) is a protein
from Homo sapiens identified by UniProt accession
Q86Y26, 1132 residues long.
MolForge cross-references it against 0 known binders and
312 disease associations.
Target properties
| Protein name | NUT family member 1 |
|---|
| UniProt accession | Q86Y26 |
|---|
| Gene | NUTM1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 1132 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (312)
Diseases linked to this target (Open Targets).
- NUT midline carcinoma · score 0.42
- non-small cell lung carcinoma · score 0.37
- lung carcinoid tumor · score 0.37
- skin basal cell carcinoma · score 0.37
- melanoma · score 0.37
- lung adenocarcinoma · score 0.37
- nodular melanoma · score 0.37
- cutaneous melanoma · score 0.37
- large cell lung carcinoma · score 0.37
- squamous cell lung carcinoma · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86Y26-F1 | alphafold | PREDICTED | 44.68 | — |
Amino-acid sequence (1132 residues)
MASDGASALP GPDMSMKPSA APSPSPALPF LPPTSDPPDH PPREPPPQPI MPSVFSPDNP LMLSAFPSSL LVTGDGGPCL SGAGAGKVIV KVKTEGGSAE PSQTQNFILT QTALNSTAPG TPCGGLEGPA PPFVTASNVK TILPSKAVGV SQEGPPGLPP QPPPPVAQLV PIVPLEKAWP GPHGTTGEGG PVATLSKPSL GDRSKISKDV YENFRQWQRY KALARRHLSQ SPDTEALSCF LIPVLRSLAR LKPTMTLEEG LPLAVQEWEH TSNFDRMIFY EMAERFMEFE AEEMQIQNTQ LMNGSQGLSP ATPLKLDPLG PLASEVCQQP VYIPKKAASK TRAPRRRQRK AQRPPAPEAP KEIPPEAVKE YVDIMEWLVG THLATGESDG KQEEEGQQQE EEGMYPDPGL LSYINELCSQ KVFVSKVEAV IHPQFLADLL SPEKQRDPLA LIEELEQEEG LTLAQLVQKR LMALEEEEDA EAPPSFSGAQ LDSSPSGSVE DEDGDGRLRP SPGLQGAGGA ACLGKVSSSG KRAREVHGGQ EQALDSPRGM HRDGNTLPSP SSWDLQPELA APQGTPGPLG VERRGSGKVI NQVSLHQDGH LGGAGPPGHC LVADRTSEAL PLCWQGGFQP ESTPSLDAGL AELAPLQGQG LEKQVLGLQK GQQTGGRGVL PQGKEPLAVP WEGSSGAMWG DDRGTPMAQS YDQNPSPRAA GERDDVCLSP GVWLSSEMDA VGLELPVQIE EVIESFQVEK CVTEYQEGCQ GLGSRGNISL GPGETLVPGD TESSVIPCGG TVAAAALEKR NYCSLPGPLR ANSPPLRSKE NQEQSCETVG HPSDLWAEGC FPLLESGDST LGSSKETLPP TCQGNLLIMG TEDASSLPEA SQEAGSRGNS FSPLLETIEP VNILDVKDDC GLQLRVSEDT CPLNVHSYDP QGEGRVDPDL SKPKNLAPLQ ESQESYTTGT PKATSSHQGL GSTLPRRGTR NAIVPRETSV SKTHRSADRA KGKEKKKKEA EEEDEELSNF AYLLASKLSL SPREHPLSPH HASGGQGSQR ASHLLPAGAK GPSKLPYPVA KSGKRALAGG PAPTEKTPHS GAQLGVPREK PLALGVVRPS QPRKRRCDSF VTGRRKKRRR SQ
Explore NUT family member 1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets