Peptidyl-tRNA hydrolase (PTRH1)

About Peptidyl-tRNA hydrolase

Peptidyl-tRNA hydrolase (PTRH1) is a protein from Homo sapiens identified by UniProt accession Q86Y79, 214 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.

Target properties

Protein name	Peptidyl-tRNA hydrolase
UniProt accession	Q86Y79
Gene	PTRH1
Organism	Homo sapiens
Length	214 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86Y79-F1	alphafold	PREDICTED	89.17	—

Amino-acid sequence (214 residues)

MRPGGFLGAG QRLSRAMSRC VLEPRPPGKR WMVAGLGNPG LPGTRHSVGM AVLGQLARRL GVAESWTRDR HCAADLALAP LGDAQLVLLR PRRLMNANGR SVARAAELFG LTAEEVYLVH DELDKPLGRL ALKLGGSARG HNGVRSCISC LNSNAMPRLR VGIGRPAHPE AVQAHVLGCF SPAEQELLPL LLDRATDLIL DHIRERSQGP SLGP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards