Histone-lysine N-methyltransferase KMT5C (KMT5C)

About Histone-lysine N-methyltransferase KMT5C

Histone-lysine N-methyltransferase KMT5C (KMT5C) is a protein from Homo sapiens identified by UniProt accession Q86Y97, 462 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.

Target properties

Protein name	Histone-lysine N-methyltransferase KMT5C
UniProt accession	Q86Y97
Gene	KMT5C
Organism	Homo sapiens
Length	462 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86Y97-F1	alphafold	PREDICTED	68.11	—

Amino-acid sequence (462 residues)

MGPDRVTARE LCENDDLATS LVLDPYLGFR THKMNVSPVP PLRRQQHLRS ALETFLRQRD LEAAYRALTL GGWTARYFQS RGPRQEAALK THVYRYLRAF LPESGFTILP CTRYSMETNG AKIVSTRAWK KNEKLELLVG CIAELREADE GLLRAGENDF SIMYSTRKRS AQLWLGPAAF INHDCKPNCK FVPADGNAAC VKVLRDIEPG DEVTCFYGEG FFGEKNEHCE CHTCERKGEG AFRTRPREPA LPPRPLDKYQ LRETKRRLQQ GLDSGSRQGL LGPRACVHPS PLRRDPFCAA CQPLRLPACS ARPDTSPLWL QWLPQPQPRV RPRKRRRPRP RRAPVLSTHH AARVSLHRWG GCGPHCRLRG EALVALGQPP HARWAPQQDW HWARRYGLPY VVRVDLRRLA PAPPATPAPA GTPGPILIPK QALAFAPFSP PKRLRLVVSH GSIDLDVGGE EL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards