PHD finger protein 13 (PHF13)

About PHD finger protein 13

PHD finger protein 13 (PHF13) is a protein from Homo sapiens identified by UniProt accession Q86YI8, 300 residues long. MolForge cross-references it against 0 known binders and 126 disease associations.

Target properties

Protein name	PHD finger protein 13
UniProt accession	Q86YI8
Gene	PHF13
Organism	Homo sapiens
Length	300 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (126)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.52
type 2 diabetes mellitus · score 0.25
Agents acting on the renin-angiotensin system use measurement · score 0.23
HMG CoA reductase inhibitor use measurement · score 0.22
mean reticulocyte volume · score 0.22
body mass index · score 0.21
sex hormone-binding globulin measurement · score 0.19
blood pressure · score 0.19
FEV/FVC ratio · score 0.18
cardiovascular disease · score 0.18

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86YI8-F1	alphafold	PREDICTED	64.10	—

Amino-acid sequence (300 residues)

MDSDSCAAAF HPEEYSPSCK RRRTVEDFNK FCTFVLAYAG YIPYPKEELP LRSSPSPANS TAGTIDSDGW DAGFSDIASS VPLPVSDRCF SHLQPTLLQR AKPSNFLLDR KKTDKLKKKK KRKRRDSDAP GKEGYRGGLL KLEAADPYVE TPTSPTLQDI PQAPSDPCSG WDSDTPSSGS CATVSPDQVK EIKTEGKRTI VRQGKQVVFR DEDSTGNDED IMVDSDDDSW DLVTCFCMKP FAGRPMIECN ECHTWIHLSC AKIRKSNVPE VFVCQKCRDS KFDIRRSNRS RTGSRKLFLD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards