About Dolichyldiphosphatase 1
Dolichyldiphosphatase 1 (DOLPP1) is a protein
from Homo sapiens identified by UniProt accession
Q86YN1, 238 residues long.
MolForge cross-references it against 0 known binders and
20 disease associations.
Target properties
| Protein name | Dolichyldiphosphatase 1 |
|---|
| UniProt accession | Q86YN1 |
|---|
| Gene | DOLPP1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 238 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (20)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.30
- schizoaffective disorder · score 0.07
- hemoglobin measurement · score 0.07
- erythrocyte count · score 0.05
- protein measurement · score 0.05
- hypersomnia · score 0.04
- blood metabolite measurement · score 0.04
- atopic eczema · score 0.03
- red blood cell density measurement · score 0.03
- Red cell distribution width · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86YN1-F1 | alphafold | PREDICTED | 89.40 | — |
Amino-acid sequence (238 residues)
MAADGQCSLP ASWRPVTLTH VEYPAGDLSG HLLAYLSLSP VFVIVGFVTL IIFKRELHTI SFLGGLALNE GVNWLIKNVI QEPRPCGGPH TAVGTKYGMP SSHSQFMWFF SVYSFLFLYL RMHQTNNARF LDLLWRHVLS LGLLAVAFLV SYSRVYLLYH TWSQVLYGGI AGGLMAIAWF IFTQEVLTPL FPRIAAWPVS EFFLIRDTSL IPNVLWFEYT VTRAEARNRQ RKLGTKLQ
Explore Dolichyldiphosphatase 1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets