About POTE ankyrin domain family member D
POTE ankyrin domain family member D (POTED) is a protein
from Homo sapiens identified by UniProt accession
Q86YR6, 584 residues long.
MolForge cross-references it against 0 known binders and
23 disease associations.
Target properties
| Protein name | POTE ankyrin domain family member D |
|---|
| UniProt accession | Q86YR6 |
|---|
| Gene | POTED |
|---|
| Organism | Homo sapiens |
|---|
| Length | 584 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (23)
Diseases linked to this target (Open Targets).
- inflammatory biomarker measurement · score 0.17
- YKL40 measurement · score 0.17
- visual perception measurement · score 0.14
- viral load · score 0.14
- cancer · score 0.03
- colorectal carcinoma · score 0.02
- neoplasm · score 0.02
- lung adenocarcinoma · score 0.01
- colorectal neoplasm · score 0.01
- breast cancer · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86YR6-F1 | alphafold | PREDICTED | 68.53 | — |
Amino-acid sequence (584 residues)
MVAEVCSMPT ASTVKKPFDL RSKMGKWCHH RFPCCRGSGK SNMGTSGDHD DSFMKMLRSK MGKCCRHCFP CCRGSGTSNV GTSGDHENSF MKMLRSKMGK WCCHCFPCCR GSGKSNVGAW GDYDHSAFME PRYHIRREDL DKLHRAAWWG KVPRKDLIVM LRDTDMNKRD KEKRTALHLA SANGNSEVVQ LLLDRRCQLN VLDNKKRTAL IKAIQCQEDE CVLMLLEHGA DRNIPDEYGN TALHYAIYNE DKLMAKALLL YGADIESKNK CGLTPLLLGV HEQKQQVVKF LIKKKANLNV LDRYGRTALI LAVCCGSASI VNLLLEQNVD VSSQDLSGQT AREYAVSSHH HVICELLSDY KEKQMLKISS ENSNPEQDLK LTSEEESQRL KVSENSQPEK MSQEPEINKD CDREVEEEIK KHGSNPVGLP ENLTNGASAG NGDDGLIPQR RSRKPENQQF PDTENEEYHS DEQNDTRKQL SEEQNTGISQ DEILTNKQKQ IEVAEQKMNS ELSLSHKKEE DLLRENSVLQ EEIAMLRLEL DETKHQNQLR ENKILEEIES VKEKTDKLLR AMQLNEEALT KTNI
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