About Rab11 family-interacting protein 4
Rab11 family-interacting protein 4 (RAB11FIP4) is a protein
from Homo sapiens identified by UniProt accession
Q86YS3, 637 residues long.
MolForge cross-references it against 0 known binders and
67 disease associations.
Target properties
| Protein name | Rab11 family-interacting protein 4 |
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| UniProt accession | Q86YS3 |
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| Gene | RAB11FIP4 |
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| Organism | Homo sapiens |
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| Length | 637 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (67)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.46
- bone quantitative ultrasound measurement · score 0.37
- cortical surface area measurement · score 0.34
- risk-taking behaviour · score 0.33
- body height · score 0.30
- brain measurement · score 0.26
- bone density · score 0.25
- keratoconus · score 0.23
- hip circumference · score 0.15
- sex hormone-binding globulin measurement · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86YS3-F1 | alphafold | PREDICTED | 70.70 | — |
Amino-acid sequence (637 residues)
MAGGAGWSGA PAALLRSVRR LREVFEVCGR DPDGFLRVER VAALGLRFGQ GEEVEKLVKY LDPNDLGRIN FKDFCRGVFA MKGCEELLKD VLSVESAGTL PCAPEIPDCV EQGSEVTGPT FADGELIPRE PGFFPEDEEE AMTLAPPEGP QELYTDSPME STQSLEGSVG SPAEKDGGLG GLFLPEDKSL VHTPSMTTSD LSTHSTTSLI SNEEQFEDYG EGDDVDCAPS SPCPDDETRT NVYSDLGSSV SSSAGQTPRK MRHVYNSELL DVYCSQCCKK INLLNDLEAR LKNLKANSPN RKISSTAFGR QLMHSSNFSS SNGSTEDLFR DSIDSCDNDI TEKVSFLEKK VTELENDSLT NGDLKSKLKQ ENTQLVHRVH ELEEMVKDQE TTAEQALEEE ARRHREAYGK LEREKATEVE LLNARVQQLE EENTELRTTV TRLKSQTEKL DEERQRMSDR LEDTSLRLKD EMDLYKRMMD KLRQNRLEFQ KEREATQELI EDLRKELEHL QMYKLDCERP GRGRSASSGL GEFNARAREV ELEHEVKRLK QENYKLRDQN DDLNGQILSL SLYEAKNLFA AQTKAQSLAA EIDTASRDEL MEALKEQEEI NFRLRQYMDK IILAILDHNP SILEIKH
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