About Hornerin
Hornerin (HRNR) is a protein
from Homo sapiens identified by UniProt accession
Q86YZ3, 2850 residues long.
MolForge cross-references it against 0 known binders and
86 disease associations.
Target properties
| Protein name | Hornerin |
|---|
| UniProt accession | Q86YZ3 |
|---|
| Gene | HRNR |
|---|
| Organism | Homo sapiens |
|---|
| Length | 2850 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (86)
Diseases linked to this target (Open Targets).
- atopic eczema · score 0.35
- Eczematoid dermatitis · score 0.30
- vitamin D measurement · score 0.29
- skin disease · score 0.28
- asthma · score 0.28
- dermatitis · score 0.26
- allergic disease · score 0.26
- childhood onset asthma · score 0.25
- age at onset · score 0.21
- hematologic disease · score 0.21
3D Structure (9)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
Amino-acid sequence (2850 residues)
MPKLLQGVIT VIDVFYQYAT QHGEYDTLNK AELKELLENE FHQILKNPND PDTVDIILQS LDRDHNKKVD FTEYLLMIFK LVQARNKIIG KDYCQVSGSK LRDDTHQHQE EQEETEKEEN KRQESSFSHS SWSAGENDSY SRNVRGSLKP GTESISRRLS FQRDFSGQHN SYSGQSSSYG EQNSDSHQSS GRGQCGSGSG QSPNYGQHGS GSGQSSSNDT HGSGSGQSSG FSQHKSSSGQ SSGYSQHGSG SGHSSGYGQH GSRSGQSSRG ERHRSSSGSS SSYGQHGSGS RQSLGHGRQG SGSRQSPSHV RHGSGSGHSS SHGQHGSGSS YSYSRGHYES GSGQTSGFGQ HESGSGQSSG YSKHGSGSGH SSSQGQHGST SGQASSSGQH GSSSRQSSSY GQHESASRHS SGRGQHSSGS GQSPGHGQRG SGSGQSPSSG QHGTGFGRSS SSGPYVSGSG YSSGFGHHES SSEHSSGYTQ HGSGSGHSSG HGQHGSRSGQ SSRGERQGSS AGSSSSYGQH GSGSRQSLGH SRHGSGSGQS PSPSRGRHES GSRQSSSYGP HGYGSGRSSS RGPYESGSGH SSGLGHQESR SGQSSGYGQH GSSSGHSSTH GQHGSTSGQS SSCGQHGATS GQSSSHGQHG SGSSQSSRYG QQGSGSGQSP SRGRHGSDFG HSSSYGQHGS GSGWSSSNGP HGSVSGQSSG FGHKSGSGQS SGYSQHGSGS SHSSGYRKHG SRSGQSSRSE QHGSSSGLSS SYGQHGSGSH QSSGHGRQGS GSGHSPSRVR HGSSSGHSSS HGQHGSGTSC SSSCGHYESG SGQASGFGQH ESGSGQGYSQ HGSASGHFSS QGRHGSTSGQ SSSSGQHDSS SGQSSSYGQH ESASHHASGR GRHGSGSGQS PGHGQRGSGS GQSPSYGRHG SGSGRSSSSG RHGSGSGQSS GFGHKSSSGQ SSGYTQHGSG SGHSSSYEQH GSRSGQSSRS EQHGSSSGSS SSYGQHGSGS RQSLGHGQHG SGSGQSPSPS RGRHGSGSGQ SSSYGPYRSG SGWSSSRGPY ESGSGHSSGL GHRESRSGQS SGYGQHGSSS GHSSTHGQHG STSGQSSSCG QHGASSGQSS SHGQHGSGSS QSSGYGRQGS GSGQSPGHGQ RGSGSRQSPS YGRHGSGSGR SSSSGQHGSG LGESSGFGHH ESSSGQSSSY SQHGSGSGHS SGYGQHGSRS GQSSRGERHG SSSGSSSHYG QHGSGSRQSS GHGRQGSGSG HSPSRGRHGS GLGHSSSHGQ HGSGSGRSSS RGPYESRSGH SSVFGQHESG SGHSSAYSQH GSGSGHFCSQ GQHGSTSGQS STFDQEGSST GQSSSYGHRG SGSSQSSGYG RHGAGSGQSP SRGRHGSGSG HSSSYGQHGS GSGWSSSSGR HGSGSGQSSG FGHHESSSWQ SSGCTQHGSG SGHSSSYEQH GSRSGQSSRG ERHGSSSGSS SSYGQHGSGS RQSLGHGQHG SGSGQSPSPS RGRHGSGSGQ SSSYSPYGSG SGWSSSRGPY ESGSSHSSGL GHRESRSGQS SGYGQHGSSS GHSSTHGQHG STSGQSSSCG QHGASSGQSS SHGQHGSGSS QSSGYGRQGS GSGQSPGHGQ RGSGSRQSPS YGRHGSGSGR SSSSGQHGSG LGESSGFGHH ESSSGQSSSY SQHGSGSGHS SGYGQHGSRS GQSSRGERHG SSSRSSSRYG QHGSGSRQSS GHGRQGSGSG QSPSRGRHGS GLGHSSSHGQ HGSGSGRSSS RGPYESRSGH SSVFGQHESG SGHSSAYSQH GSGSGHFCSQ GQHGSTSGQS STFDQEGSST GQSSSHGQHG SGSSQSSSYG QQGSGSGQSP SRGRHGSGSG HSSSYGQHGS GSGWSSSSGR HGSGSGQSSG FGHHESSSWQ SSGYTQHGSG SGHSSSYEQH GSRSGQSSRG EQHGSSSGSS SSYGQHGSGS RQSLGHGQHG SGSGQSPSPS RGRHGSGSGQ SSSYGPYGSG SGWSSSRGPY ESGSGHSSGL GHRESRSGQS SGYGQHGSSS GHSSTHGQHG SASGQSSSCG QHGASSGQSS SHGQHGSGSS QSSGYGRQGS GSGQSPGHGQ RGSGSRQSPS YGRHGSGSGR SSSSGQHGPG LGESSGFGHH ESSSGQSSSY SQHGSGSGHS SGYGQHGSRS GQSSRGERHG SSSGSSSRYG QHGSGSRQSS GHGRQGSGSG HSPSRGRHGS GSGHSSSHGQ HGSGSGRSSS RGPYESRSGH SSVFGQHESG SGHSSAYSQH GSGSGHFCSQ GQHGSTSGQS STFDQEGSST GQSSSHGQHG SGSSQSSSYG QQGSGSGQSP SRGRHGSGSG HSSSYGQHGS GSGWSSSSGR HGSGSGQSSG FGHHESSSWQ SSGYTQHGSG SGHSSSYEQH GSRSGQSSRG ERHGSSSGSS SSYGQHGSGS RQSLGHGQHG SGSGQSPSPS RGRHGSGSGQ SSSYSPYGSG SGWSSSRGPY ESGSGHSSGL GHRESRSGQS SGYGQHGSSS GHSSTHGQHG STSGQSSSCG QHGASSGQSS SHGQHGSGSS QSSGYGRQGS GSGQSPGHGQ RGSGSRQSPS YGRHGSGSGR SSSSGQHGSG LGESSGFGHH ESSSGQSSSY SQHGSGSGHS SGYGQHGSRS GQSSRGERHG SSSGSSSHYG QHGSGSRQSS GHGRQGSGSG QSPSRGRHGS GLGHSSSHGQ HGSGSGRSSS RGPYESRLGH SSVFGQHESG SGHSSAYSQH GSGSGHFCSQ GQHGSTSGQS STFDQEGSST GQSSSYGHRG SGSSQSSGYG RHGAGSGQSL SHGRHGSGSG QSSSYGQHGS GSGQSSGYSQ HGSGSGQDGY SYCKGGSNHD GGSSGSYFLS FPSSTSPYEY VQEQRCYFYQ
Explore Hornerin with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets