About Complement C1q-like protein 4
Complement C1q-like protein 4 (C1QL4) is a protein
from Homo sapiens identified by UniProt accession
Q86Z23, 238 residues long.
MolForge cross-references it against 0 known binders and
22 disease associations.
Target properties
| Protein name | Complement C1q-like protein 4 |
|---|
| UniProt accession | Q86Z23 |
|---|
| Gene | C1QL4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 238 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (22)
Diseases linked to this target (Open Targets).
- visual perception measurement · score 0.20
- breast cancer · score 0.08
- Obesity · score 0.06
- hemoglobin D disease · score 0.03
- diabetes mellitus, permanent neonatal 4 · score 0.03
- MODY · score 0.03
- permanent neonatal diabetes mellitus 1 · score 0.03
- diabetes mellitus · score 0.02
- platelet component distribution width · score 0.02
- non-small cell lung carcinoma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86Z23-F1 | alphafold | PREDICTED | 80.33 | — |
Amino-acid sequence (238 residues)
MVLLLLVAIP LLVHSSRGPA HYEMLGRCRM VCDPHGPRGP GPDGAPASVP PFPPGAKGEV GRRGKAGLRG PPGPPGPRGP PGEPGRPGPP GPPGPGPGGV APAAGYVPRI AFYAGLRRPH EGYEVLRFDD VVTNVGNAYE AASGKFTCPM PGVYFFAYHV LMRGGDGTSM WADLMKNGQV RASAIAQDAD QNYDYASNSV ILHLDVGDEV FIKLDGGKVH GGNTNKYSTF SGFIIYPD
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