About Interferon lambda-1
Interferon lambda-1 (IFNL1) is a protein
from Homo sapiens identified by UniProt accession
Q8IU54, 200 residues long.
MolForge cross-references it against 0 known binders and
205 disease associations.
Target properties
| Protein name | Interferon lambda-1 |
|---|
| UniProt accession | Q8IU54 |
|---|
| Gene | IFNL1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 200 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (205)
Diseases linked to this target (Open Targets).
- thyroid gland adenocarcinoma · score 0.23
- ulcerative colitis · score 0.12
- Rheumatoid arthritis · score 0.10
- Systemic lupus erythematosus · score 0.09
- COVID-19 · score 0.09
- infection · score 0.09
- infect · score 0.09
- microphthalmia with limb anomalies · score 0.08
- systemic lupus erythematosus · score 0.07
- periodontitis · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IU54-F1 | alphafold | PREDICTED | 82.82 | — |
Amino-acid sequence (200 residues)
MAAAWTVVLV TLVLGLAVAG PVPTSKPTTT GKGCHIGRFK SLSPQELASF KKARDALEES LKLKNWSCSS PVFPGNWDLR LLQVRERPVA LEAELALTLK VLEAAAGPAL EDVLDQPLHT LHHILSQLQA CIQPQPTAGP RPRGRLHHWL HRLQEAPKKE SAGCLEASVT FNLFRLLTRD LKYVADGNLC LRTSTHPEST
Explore Interferon lambda-1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets