Keratin-associated protein 19-1 (KRTAP19-1)

About Keratin-associated protein 19-1

Keratin-associated protein 19-1 (KRTAP19-1) is a protein from Homo sapiens identified by UniProt accession Q8IUB9, 90 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.

Target properties

Protein name	Keratin-associated protein 19-1
UniProt accession	Q8IUB9
Gene	KRTAP19-1
Organism	Homo sapiens
Length	90 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (8)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.42
glioblastoma multiforme · score 0.18
head and neck squamous cell carcinoma · score 0.18
esophageal cancer · score 0.14
gastric carcinoma · score 0.01
cancer · score 0.00
rosacea · score 0.00
atopic eczema · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8IUB9-F1	alphafold	PREDICTED	49.36	—

Amino-acid sequence (90 residues)

MSHYGSYYGG LGYSCGGFGG LGYGYGCGCG SFCRRGSGCG YGGYGYGSGF GSYGYGSGFG GYGYGSGFGG YGYGCCRPSY NGGYGFSGFY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards