About Keratin-associated protein 1-3
Keratin-associated protein 1-3 (KRTAP1-3) is a protein
from Homo sapiens identified by UniProt accession
Q8IUG1, 167 residues long.
MolForge cross-references it against 0 known binders and
21 disease associations.
Target properties
| Protein name | Keratin-associated protein 1-3 |
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| UniProt accession | Q8IUG1 |
|---|
| Gene | KRTAP1-3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 167 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (21)
Diseases linked to this target (Open Targets).
- glioblastoma multiforme · score 0.18
- clear cell renal carcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- attention deficit hyperactivity disorder · score 0.06
- Tourette syndrome · score 0.05
- sebaceous of Jadassohn nevus · score 0.05
- schizophrenia 15 · score 0.04
- Phelan-McDermid syndrome · score 0.04
- metabolite measurement · score 0.04
- Potocki-Lupski syndrome · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IUG1-F1 | alphafold | PREDICTED | 41.84 | — |
Amino-acid sequence (167 residues)
MTCCQTSFCG YPSCSTSGTC GSSCCQPSCC ETSCCQPSCC QTSFCGFPSF STSGTCSSSC CQPSCCETSC CQPSCCQTSS CGTGCGIGGG IGYGQEGSSG AVSTRIRWCR PDCRVEGTCL PPCCVVSCTP PTCCQLHHAE ASCCRPSYCG QSCCRPVCCC YSCEPTC
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