About Protein CREG2
Protein CREG2 (CREG2) is a protein
from Homo sapiens identified by UniProt accession
Q8IUH2, 290 residues long.
MolForge cross-references it against 0 known binders and
26 disease associations.
Target properties
| Protein name | Protein CREG2 |
|---|
| UniProt accession | Q8IUH2 |
|---|
| Gene | CREG2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 290 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (26)
Diseases linked to this target (Open Targets).
- central nervous system cancer · score 0.04
- exercise-induced hyperinsulinism · score 0.03
- glioblastoma multiforme · score 0.03
- erythrocyte count · score 0.03
- astrocytoma · score 0.03
- oligodendroglioma · score 0.03
- non-small cell lung carcinoma · score 0.03
- ependymoma · score 0.03
- ST2 protein measurement · score 0.02
- medulloblastoma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IUH2-F1 | alphafold | PREDICTED | 71.86 | — |
Amino-acid sequence (290 residues)
MSVRRGRRPA RPGTRLSWLL CCSALLSPAA GYVIVSSVSW AVTNEVDEEL DSASTEEAMP ALLEDSGSIW QQSFPASAHK EDAHLRPRAG AARARPPPAP PGMFSYRREG GQTASAPPGP RLRAATARSL AHASVWGCLA TVSTHKKIQG LPFGNCLPVS DGPFNNSTGI PFFYMTAKDP VVADLMKNPM ASLMLPESEG EFCRKNIVDP EDPRCVQLTL TGQMIAVSPE EVEFAKQAMF SRHPGMRKWP RQYEWFFMKM RIEHIWLQKW YGGASSISRE EYFKAVPRKA
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