About Leucine rich adaptor protein 1-like
Leucine rich adaptor protein 1-like (LURAP1L) is a protein
from Homo sapiens identified by UniProt accession
Q8IV03, 228 residues long.
MolForge cross-references it against 0 known binders and
39 disease associations.
Target properties
| Protein name | Leucine rich adaptor protein 1-like |
|---|
| UniProt accession | Q8IV03 |
|---|
| Gene | LURAP1L |
|---|
| Organism | Homo sapiens |
|---|
| Length | 228 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (39)
Diseases linked to this target (Open Targets).
- sunburn · score 0.34
- Tracheoesophageal fistula · score 0.26
- hair colour measurement · score 0.16
- cutaneous melanoma · score 0.12
- hair color · score 0.12
- refractive error measurement · score 0.12
- eye color · score 0.11
- eye colour measurement · score 0.10
- body height · score 0.09
- protein measurement · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IV03-F1 | alphafold | PREDICTED | 64.60 | — |
Amino-acid sequence (228 residues)
MEDSPLPDLR DIELKLGRKV PESLVRSLRG EEPVPRERDR DPCGGSGGGG GGGGGCSSSS SYCSFPPSLS SSSSSSPTSG SPRGSHSSAL ERLETKLHLL RQEMVNLRAT DVRLMRQLLV INESIESIKW MIEEKATITS RGSSLSGSLC SLLESQSTSL RGSYNSLHDG SDGLDGISVG SYLDTLADDV PGHQTPSDLD QFSDSSLIED SQALHKRPKL DSEYYCFG
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