Cyclin-J-like protein (CCNJL)

About Cyclin-J-like protein

Cyclin-J-like protein (CCNJL) is a protein from Homo sapiens identified by UniProt accession Q8IV13, 435 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.

Target properties

Protein name	Cyclin-J-like protein
UniProt accession	Q8IV13
Gene	CCNJL
Organism	Homo sapiens
Length	435 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (25)

Diseases linked to this target (Open Targets).

diabetes mellitus · score 0.30
mean platelet volume · score 0.29
BMI-adjusted waist circumference · score 0.27
asthma · score 0.04
Eczematoid dermatitis · score 0.04
allergic rhinitis · score 0.04
body mass index · score 0.04
eosinophil count · score 0.03
allergic disease · score 0.03
systemic lupus erythematosus · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8IV13-F1	alphafold	PREDICTED	67.24	—

Amino-acid sequence (435 residues)

MMDEPWWEGR VASDVHCTLR EKELKLPTFR AHSPLLKSRR FFVDILTLLS SHCQLCPAAR HLAVYLLDHF MDRYNVTTSK QLYTVAVSCL LLANGVSLLS PRLKCSGMIS AHCNLHLPGS SNSPASAPHP PPTPPQVAET TGKFEDREDH VPKLEQINST RILSSQNFTL TKKELLSTEL LLLEAFSWNL CLPTPAHFLD YYLLASVSQK DHHCHTWPTT CPRKTKECLK EYAHYFLEVT LQDHIFYKFQ PSVVAAACVG ASRICLQLSP YWTRDLQRIS SYSLEHLSTC IEILLVVYDN VLKDAVAVKS QALAMVPGTP PTPTQVLFQP PAYPALGQPA TTLAQFQTPV QDLCLAYRDS LQAHRSGSLL SGSTGSSLHT PYQPLQPLDM CPVPVPASLS MHMAIAAEPR HCLATTYGSS YFSGSHMFPT GCFDR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards